Healthcare Innovations and Translational Informatics lab (HITI) @ Emory


Machine learning for Health, Imaging Informatics

Neurofibromatosis Type I AI assisted reporting



Neurofibromatosis type 1 is a condition characterized by changes in skin coloring (pigmentation) and the growth of tumors along nerves in the skin, brain, and other parts of the body.  Most adults with neurofibromatosis type 1 develop neurofibromas, which are noncancerous (benign) tumors that are usually located on or just under the skin. These tumors may also occur in nerves near the spinal cord or along nerves elsewhere in the body. Some people with neurofibromatosis type 1 develop cancerous tumors that grow along nerves. These tumors, which usually develop in adolescence or adulthood, are called malignant peripheral nerve sheath tumors. 
The interpretation of these studies takes a lot of manual work - trying to figure out what tumors are new, which ones are old, and what tumors are changing with a high risk of malignancy.
Your task is to assist with the diagnosis of these tumors - specifically to populate the interpretation template here - specifically for the NF1 lesions . 
For each identified NF1 related abnormality, discuss T1 and T2 signal, borders as ill-defined or circumscribed, the absence or presence of enhancement or mass effect, and any interval change since the prior studies.

As you review the template , you can identify that a lot of segmentation and anatomy identification can be performed on these MRI studies to identify areas  including the optic pathway